|IMMEDIATE GIK is an intravenous (IV) solution that is made up of three commonly available ingredients:
- G = Glucose
- Glucose, a sugar, is the major energy source of the body. It provides fuel to the heart when there is a reduced blood supply.
- I = Insulin
- Insulin is a hormone that is naturally made by the body. Insulin helps move the glucose into the cells.
- K = Potassium (The chemical element for Potassium is “K”).
- Potassium is a salt that is found in many foods and is stored in the blood. There is a potential for potassium levels to become low when glucose and insulin are infused, therefore it is essential to administer to maintain adequate levels.
Will everyone receive GIK?
Participants will receive either the study drug (GIK) or the placebo that is sugar and water (this is a standard IV solution that is normally given to heart attack patients). Which study drug solution the patient receives is determined by chance, like the flip of a coin. Neither the patient, nor the treating medical staff will know which study drug solution is given unless it is medically necessary to know.
How may GIK be helpful?
When someone has a heart attack, there is a sudden interruption or insufficient supply of oxygen-rich blood to the heart through the coronary arteries that can result in permanent damage to the heart or death. If given early, GIK may help stabilize the heart and potentially prevent further heart muscle damage until alternative treatments are available.
Is GIK dangerous?
There is a very small risk of inflammation at the site of the IV line that may cause some discomfort and irritation. Potassium levels may become elevated or lowered as a result of the infusion and that could cause palpitations, dizziness, or a change in heart beat. It is also possible that blood sugar levels may become elevated or lowered as a result of the infusion, that could cause weakness if low, or if high, it could cause weakness, dizziness or thirstiness. Additionally, the IV solution provides additional fluid. In very few people, a medication is needed to help your body get rid of the extra fluid. The medical team will monitor for these symptoms as part of standard medical care.
There are few side effects associated with GIK infusion: